Monday, November 28, 2022

Does Wine A Day Keep The Doctors Away?

     Turns out it does! Well it kind of does... Resveratrol, a well-known polyphenol, also plays a role in preventing blood clots and is found in red wine. Polyphenols are a type of antioxidant that helps to protect blood vessels from plaque buildup by maintaining a healthy level of "good" cholesterol in the body (Going, 2015). This polyphenol in particular contributes significantly to red wine's heart-healthy properties. A study on mice and pigs was conducted to determine the health benefits of resveratrol, but the study revealed that you would have to consume a very large, unreasonable amount of liters of wine to achieve the amount of resveratrol required to match the amount given to the animals. The ability of resveratrol to act as a potent antioxidant is arguably one of its most impressive biological properties, along with its ability to protect cells and mop up free radicals. However, this second characteristic in some studies suggest resveratrol may behave as a pro-oxidizing agent. Resveratrol's actions on theca-interstitial cells of the ovary, which are responsible for ovarian follicle growth and maturation, include antiproliferative and androgen-lowering properties, in addition to its well-known cardioprotective, antioxidant, anticancer, neuroprotective, anti-inflammatory, anti-dyslipidemia, and antidiabetic properties (Salehi, 2018). Ironically, it may also have importance in the pathology of numerous disorders, as it has been shown in some research to behave as a pro-oxidizing agent. More research on this compound is needed to determine its true benefits and whether these benefits outweigh the negative effects that alcohol/red wine may have.

    Red wine was also linked to a lower risk of incident depression, according to the study's findings (Gea, 2013). This study was well-conducted, and its findings piqued my curiosity; if you're similarly inclined, I recommend reading up on it (listed in citations). There are many aspects of red wine that I did not cover, and I concentrated on the antioxidant aspect of red wine because it contains so many of the health benefits that red wine provides.

    In conclusion, red wine has numerous of health benefits; even so, red wine should be consumed in moderation and responsibly. The benefits of red wine do not always occur depending on your personal situation and health history. 


Citations:

Salehi B, Mishra AP, Nigam M, Sener B, Kilic M, Sharifi-Rad M, Fokou PVT, Martins N, Sharifi-Rad J. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018 Sep 9;6(3):91. doi: 10.3390/biomedicines6030091. PMID: 30205595; PMCID: PMC6164842.

Gea A, Beunza JJ, Estruch R, Sánchez-Villegas A, Salas-Salvadó J, Buil-Cosiales P, Gómez-Gracia E, Covas MI, Corella D, Fiol M, Arós F, Lapetra J, Lamuela-Raventós RM, Wärnberg J, Pintó X, Serra-Majem L, Martínez-González MA; PREDIMED GROUP. Alcohol intake, wine consumption and the development of depression: the PREDIMED study. BMC Med. 2013 Aug 30;11:192. doi: 10.1186/1741-7015-11-192. PMID: 23988010; PMCID: PMC3765610.

Going, C. E. (2015, November 3). Does A Glass of Wine A Day Keep the Doctor Away? | SiOWfa15: Science in Our World: Certainty and Controversy. Does a Glass of Wine a Day Keep the Doctor Away? | SiOWfa15: Science in Our World: Certainty and Controversy. Retrieved November 28, 2022, from https://sites.psu.edu/siowfa15/2015/11/02/does-a-glass-of-wine-a-day-keep-the-doctor-away/

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